PRODUCT IDENTIFICATION
CLASSIFICATION
PHYSICAL AND CHEMICAL PROPERTIES
Reacts
AUTOIGNITION
NFPA RATINGS
REFRACTIVE INDEX
FLASH POINT
GENERAL DESCRIPTION & APPLICATIONS
APPEARANCE
95% min (or 0.5M solution in toluene or tetrahydrofuran)
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| POTASSIUM HEXAMETHYLDISILAZANE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 40949-94-8 |
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| EINECS NO. | ||
| FORMULA | [(CH3)3Si]2NK | |
| MOL WT. | 199.48 | |
| H.S. CODE | ||
| TOXICITY | ||
| SYNONYMS | Hexamethyldisilazane potassium salt; KHMDS; | |
| Potassium bis(trimethylsilyl)amide; Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-, potassium salt | ||
| SMILES | ||
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | off-white crystalline powder | |
| MELTING POINT | ||
| BOILING POINT | ||
| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER |
Reacts | |
| pH | ||
| VAPOR DENSITY | ||
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AUTOIGNITION |
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NFPA RATINGS |
Health: 3 Flammability: 0 Reactivity: 0 | |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY | Stable under ordinary conditions. Moisture sensitive | |
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GENERAL DESCRIPTION & APPLICATIONS |
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| Hexamethyldisilazane (HMDS) is a strong hindered amine base but non-nucleophile (called harpoon base). The formula is (CH3)3Si-NH-Si(CH3)3 which consists of ammonia substituted with two trimethylsilyl groups. Silicon-consist alkali metal amides, such as Lithium hexamethyldisilazide (LiHMDS), Sodium hexamethyldisilazide (NaHMDS) are harpoon bases which are involved in kinetic deprotonation as the electron donor abstracts a proton. The advantages are that it is available as a solid and it is soluble in a wide range of nonpolar solvents. They are widely used in chemical reactions and transformation including Alkylation, base catalyzed reaction, condensation, dehalogenenation, deprotonations. elimination reaction, enolate formation, isomerization reaction, polymer application, selective metalation, super base application and transesterfication. Orher examples are Lithium diisopropylamide, Lithium tetramethylpiperidide, and alkali metal alcoholates. | ||
| SALES SPECIFICATION | ||
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APPEARANCE |
off-white crystalline powder | |
| ASSAY |
95% min (or 0.5M solution in toluene or tetrahydrofuran) | |
| TRANSPORTATION | ||
| PACKING | ||
| HAZARD CLASS | 3 (Packing Group: II) | |
| UN NO. | 2924 | |
| OTHER INFORMATION | ||
| Hazard Symbols: C, Risk Phrases: 34, Safety Phrases: 25-28-36/37/39 | ||
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